Bomber is an unemployed boat captain. One day he meets Jerry, a manager of boxers who are struck by the force of his fists. That is when they see the chance to win big money.

Trinity series star Bud Spencer returns to the Wild West in director Michele Lupo's comic tale of an outlaw drifter, Buddy, who is mistaken for a doctor after his Indian companion inadvertently steals a bag of surgical instruments. When a band of murderous outlaws attempts to overrun the small town Buddy is passing through, the presumed medico shows that his true talent is cracking skulls. Music is composed by Ennio Morricone.