Two detectives who are up to their necks in trouble and in each other's face, as they try to shut down a drug-trafficking scheme that could be connected with international ties to organized crime. But in the midst of their investigation, innocent immigrant dock worker Luk Wan-Ting gets caught up in the mix when he witnesses the murder of an intelligence operative and is framed for the crime.

When Dr. Yuen attempts to rescue a girl about to be sacrificed by the Worm Tribe in the middle of a jungle in Thailand, he is damned with seven 'blood curses' and must return there to find a permanent cure.