A nameless, pill-popping drifter girl steps off a bus and into a New Jersey neighborhood bar owned by two middle-age brothers, Jimmy & Victor. She quickly befriends older brother, Victor––a good-natured lummox whose mind was affected by a childhood accident. The mysterious "Girl" soon upsets the delicate balance of the brothers' lives while bringing both trouble and new life into their resigned world and town.

Bourne is brought out of hiding once again by reporter Simon Ross who is trying to unveil Operation Blackbriar, an upgrade to Project Treadstone, in a series of newspaper columns. Information from the reporter stirs a new set of memories, and Bourne must finally uncover his dark past while dodging The Company's best efforts to eradicate him.