The medical drama focuses on the lives of doctors and nurses who are members of an elite medical team from the fictional Gwang Hae University Hospital.
Jung Yi-hyun is a genius, but she suffers from psychogenic amnesia and does not remember her husband and young daughter. Hong Gyung-doo is uneducated and poor, but he's a loving father to young Hae-deum, who's inherited her genius from her mother. Yi-hyun and Gyung-doo met just as both were on the brink of suicide, and they'd decided to choose life together. The drama is about Yi-hyun's journey to putting together the pieces of her lost memory with her husband's help, a man who seems completely unsuited for her.
The assistant of a wealthy socialite reveals her husband's salacious affair. The fallout entangles him in a web of sex, love and deceit that could threaten his life and career.