The story of Padre Pio (1887-1968) from the onset of the stigmata during World War I, when he prayed that soldiers' suffering be his, until his death. The story is told by Emilia, Pio's friend, to a Vatican official reviewing Padre Pio's potential canonization. We watch local people venerate the humble Capuchin monk, we see petty jealousies within the Church almost bring him down, and we experience his decision to build a Home for the Relief of Suffering, a labor of love begun just after World War II. Emilia and her husband Dr. Sanguineti work tirelessly beside the humble but sensible Pio.

Don Matteo is a thoroughly ordinary Catholic priest with an extraordinary ability to read people and solve crimes. He’s a parish priest who never met an unjustly accused person he didn’t want to help.

After his father's death, a middle-aged screenwriter struggles with his obsessions and neuroses.

The freshly graduated psychiatrist David shall deliver an opinion about young Maddalena, who's on trial for murdering a hunter. She claims she's a witch and acted on behalf of the devil.