After telling her fiancé, Dana, that her entire family is dead, Manhattanite Alex whisks off to her childhood home in South Carolina to serve as bridesmaid at her high-maintenance, estranged sister Jeannie's wedding. As she tries not to steal Jeannie's thunder by telling her family that a) she's engaged, and b) the man she's going to marry is a Jewish African American, things get a little mixed up.

When they're sent to the tiny backwoods town of Little Hope to collect market research interviews, co-working opposites Linda and Kelly find there's literally no room at the inn, and they're forced to stay together at a local youth hostel. But sharing such a tight space produces interesting results.