Lucky Luke becomes the Sheriff of Daisy Town and runs out all the criminals. Then the Dalton brothers arrive and try to get the Indians to break the peace treaty and attack the town.

Confined to his bed in an asylum for the criminally insane, Billy Boy Shrank is no ordinary man: he's a decomposing, moronic, telepathic cannibal. He's also a victim of unrequited love for Reena, an angry young punk, leader of a dedicated but fledgling all-girl rock group.