When Snoopy receives a letter from his original owner Lila, he goes to visit her in the hospital while Charlie Brown and the gang are on the lookout for him. Suddenly, Snoopy feels that he must go live with Lila, but must say goodbye to all his friends. In his adventure to the hospital, he encounters numerous "No Dogs Allowed" signs, an annoying little girl who desires to keep him, and more!

Play It Again, Charlie Brown is the seventh prime-time animated TV special based upon the popular comic strip Peanuts, by Charles M. Schulz. This non-holiday Peanuts special centers on Lucy, her infatuation with Schroeder, and her willingness to do anything to win his affections.

The successful comic strip Peanuts, by Charles M. Schulz, was adapted into animated specials since 1965, most of them released on television.