A chief-commander gynaecologist and a young and lovely team of professionals: obstetricians, neonatal doctors, paediatricians, nurses: they all have different histories, they cross their lives in this small, forgotten hospital. Together they will succeed in making it a jewel of efficiency and humanity.

In a small village of Naples three friends, Francis, Mimmo and Lello, manage to get a meeting with three beautiful Bulgarian girls known on the Internet, scheduled for Christmas. The wives alarmed try to stir the spirits of the three hot husbands, but the whole thing is just a trick of three Bulgarians with intent to deprive the people of their assets in the country and that the girls will not.

In Sicily, in a time not yet forgotten, in the heart of a small secluded town populated by cicadas, ticks and venomous snakes, that which made a man a real man was not riches or power, but his honor. He had to defend his dignity against insults and village gossip. It took little to stoke the fire once lit, and no one was immune. One of the worst humiliations a man can suffer was to have an adulterous wife. A man so disgraced would bear the mark of shame, with all eyes of the community upon him. It was said that "his horns were sticking out" for all to see.

The series tells the stories of some of the characters who work or are related to an imaginary shopping center Centovetrine, located in the center of Turin. There are many stories of love and passion, but also struggles for power and dynastic quarrels in the telefilm.

In 18th-century Sicily, deaf-mute highborn Marianna Ucrìa is forced to marry at age 13, bearing three children before even turning 16, when she finally gives birth to a boy. Despite everything, she'll find a way to emancipate herself from the oppressive social conventions of the time.