The angel Gabriel comes to Earth to collect a soul which will end the stalemated war in Heaven, and only a former priest and a little girl can stop him.

Lenore Davis and her husband Frank are about to have their second child. As she gives birth, the newborn baby vanishes and leaves behind five dead bodies. It's up to the police and Frank to figure out where their mutated child has gone.

Tommy Gibbs is a tough kid, raised in the ghetto, who aspires to be a kingpin criminal. As a young boy, his leg is broken by a bad cop on the take, during a pay-off gone bad. Nursing his vengeance, he rises to power in Harlem, New York. Angry at the racist society around him, both criminal and straight, he sees the acquisition of power as the solution to his rage.

A technician brings a frozen specimen of the original Blob back from the North Pole. When his wife accidentally defrosts the thing, it terrorizes the populace-- the local hippies, cops, drunks and bowlers must all face the Blob!