The story revolves around a Basque Roman Catholic priest dedicated to committing as many sins as possible, a death metal salesman from Carabanchel, and the Italian host of a TV show on the occult. These go on a literal "trip" through Christmas-time Madrid to hunt for and prevent the reincarnation of the Antichrist.

Waging war against all things glamorous and beautiful, crippled terrorists Acción Mutante plot a series of attacks on society's elite, and attempt the kidnapping of a wealthy socialite at her elaborate wedding reception.

Medrel was born old. His life passes between doctors and scientists. Years go by and he is even getting younger. But he lacks the most important thing: love.