Jean-Baptiste Grenouille, born in the stench of 18th century Paris, develops a superior olfactory sense, which he uses to create the world's finest perfumes. However, his work takes a dark turn as he tries to preserve scents in the search for the ultimate perfume.

Dr. Bruno Sachs, the only medical practitioner in a small French town, seems on the surface to be compassionate and dedicated. However, in private he is not happy in his work and does not like most of his patients. Here he meets Pauline Kasser, a young woman, and they are attracted to each other...