Jimi, a computer game designer, finds that his latest product has been infected by a virus which has given consciousness to the main character of the game, Solo. Tormented by the memory of his fled girlfriend Lisa and begged by Solo to end its useless "life", Jimi begins a search for people who can help him both to discover what happened to Lisa and to delete his game before it is released.

Targeted by a dirty cop after witnessing a murder, bank clerk Mario flees to Puerto Escondido, Mexico, where a couple of oddball Italian expats drags him into a journey of self-discovery and bad decisions.

Two stage actors leave on a tournée, but there's a matter to be settled: one has become the lover of the other's girlfriend and since they are very good friends, cannot bring himself to tell him.

Via Montenapoleone in Milan is the ritziest street in the city and here the destinies of several characters, playboys, models and gays cross and diverge.