An American scientist up to no good (as usual) by creating the half-pterodactyl, half-barracuda: Pteracuda. When the creature inevitably escapes, it's up to Sharktopus to stop him.

A young girl named Andrea unleashes a spirit after removing a cross on a sacred holy ground cemetery. The spirit starts terrorizing Andrea and her family. Andrea's family, witch doctors, and spiritual healers battle the spirit in attempts to return to a normal life.