Dr. Megan Hunt was in a class of her own, a brilliant neurosurgeon at the top of her game. But her world is turned upside down when a devastating car accident puts an end to her time in the operating room. Megan resumes her career as a medical examiner, determined to solve the puzzle of who or what killed the victims.

Haunted with nightmares of his wife's recent suicide and struggling to mend the relationship with his only daughter, Richard is caught as a witness to the violence of Abner Solvie. He finds himself at the mercy of a charismatic killer and plagued by his involvement in the city's recent murders. As Abner's new found protégé, Richard is forced to adopt the mind of his sociopathic mentor in order to protect the one he loves. Richard must decide if he's willing to kill in order to keep his daughter alive.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.