Following the events of Age of Ultron, the collective governments of the world pass an act designed to regulate all superhuman activity. This polarizes opinion amongst the Avengers, causing two factions to side with Iron Man or Captain America, which causes an epic battle between former allies.

A rogue soldier turned outlaw is thrust into a relentless fight with a corrupt sheriff, his obedient deputies, and a dangerous drug cartel in order to protect his sister and her young daughter.

When a frightening wave of violence sweeps through New York City, troubled cop Sarchie fails to find a rational explanation for the bizarre crimes. However, his eyes are opened to a frightening alternate reality when renegade Jesuit priest Mendoza convinces him that demonic possession may be to blame for the gruesome murders. Together, they wage a valiant supernatural struggle to rid the city of an otherworldly evil.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.