In 1934, the second most lucrative business in New York City was running 'the numbers'. When Madam Queen—the powerful woman who runs the scam in Harlem—is arrested, Ellsworth 'Bumpy' Johnson takes over the business and must resist an invasion from a merciless mobster.

A research scientist becomes the world's first pregnant man in order to test a drug he and a colleague have designed for expectant women. To carry out the trial, he has an embryo implant, believing that he will only carry the baby for three months – hardly expecting to face the prospect of giving birth.