A globe-trotting photojournalist has a secret life as a CIA field agent.

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

The exploits of the Los Angeles–based Office of Special Projects (OSP), an elite division of the Naval Criminal Investigative Service that specializes in undercover assignments.

Rules of Engagement is a comedy about the different phases of male/female relationships, as seen through the eyes of a newly engaged couple, Adam and Jennifer, a long-time married pair, Jeff and Audrey, and a single guy on the prowl, Russell. As they find out, the often confusing stages of a relationship can seem like being on a roller coaster. People can describe the ride to you, but to really know what it's like you have to experience it for yourself.

From murder and espionage to terrorism and stolen submarines, a team of special agents investigates any crime that has a shred of evidence connected to Navy and Marine Corps personnel, regardless of rank or position.