Jerry Shaw and Rachel Holloman are two strangers whose lives are suddenly thrown into turmoil by a mysterious woman they have never met. Threatening their lives and family, the unseen caller uses everyday technology to control their actions and push them into increasing danger. As events escalate, Jerry and Rachel become the country's most-wanted fugitives and must figure out what is happening to them.

Kale is a 17-year-old placed under house arrest after punching his teacher. He is confined to his house, and decides to use his free time spying on his neighbors. Things start to get weird when guests enter the Turner's house and don't come back out. Kale and his friends, Ronnie and Ashley, start to grow more and more interested in what is actually happening within the house of Robert Turner.