A mother takes her two sons on an unusual road trip from New York to Pittsburgh, St. Louis and eventually Hollywood in her quest to find a man to take care of them all.

Sylvia Stickles runs a convenience store with her husband and mother-in-law. One day, Sylvia is hit on the head and transforms from an uptight prude to a sex-crazed lunatic. As she goes on a rampage through town, Sylvia attracts the attention of Ray Ray, a sexual healer and tow truck driver in search of the world's greatest orgasm. Their sexual revolution, however, causes a class war in their tiny Baltimore community.

Having just returned from a mission to Mars, Commander Ross isn't exactly himself. He's slowly becoming a terrifying alien entity with one goal -- to procreate with human women! When countless women suffer gruesome deaths after bearing half-alien offspring, scientist Laura Baker and hired assassin Press Lennox use Eve, a more tempered alien clone, to find Ross and his brood. Before long Eve escapes to mate with Ross.

Beverly is the perfect happy homemaker, along with her doting husband and two children, but this nuclear family just might explode when her fascination with serial killers collides with her ever-so-proper code of ethics.