After his young son dies from the negligence at a hospital, Harry Fertig takes matters into his own hands and kills the doctors responsible. Slick lawyer Roy Bleakie, looking only to win a case and not caring of the matters involved, is assigned Fertig's case. Shocked to hear that his client wants to plead guilty, the case causes Bleakie to question his own morals by defending an honorable man.

Workaholic Mike Flaherty is the Deputy Mayor of New York City, serving as Mayor Randall Winston's key strategist and much-needed handler. Mike runs the city with the help of his oddball staff: an anxious and insecure press secretary; a sexist, boorish chief of staff; an impeccably groomed gay activist running minority affairs; a sharp and efficient, man-crazy accountant; and an idealistic young speechwriter. Like Mike, they are all professionally capable but personally challenged.