A young grandmother in a small Pennsylvania town raises her daughter's child after the girl disappears. All the while, a desperate search for her continues.

A young Harvard counselor, Ellen Dane, only wants to help. A yearning client, Matthew Jude, only wants to be healed. The closer they become, the further they must go until imposing one's view on another has unimagined consequences.

A medical breakthrough causes a zombie outbreak when it mutates within certain individuals in the trial injections.