Louie De Palma is a cantankerous, acerbic taxi dispatcher in New York City. He tries to maintain order over a collection of varied and strange characters who drive for him. As he bullies and insults them from the safety of his “cage,” they form a special bond among themselves, becoming friends and supporting each other through the inevitable trials and tribulations of life.

An airplane carring coffee beans from South America has some unpleasant stowaways: a hoard of tarantulas which overcome the pilots as the airplane is flying over an orange-producing town in California. The airplane crashes, and the unlucky inhabitants of the town release the poisonous spiders into their midst. Once the town's officials discover that the tarantulas are responsible for several deaths, the tarantulas have already descended upon the town's only orange-processing factory. The town's citizens risk their lives to remove the tarantulas from the factory while the poisonous pests are rendered motionless by the transmitted sound of buzzing bees

During an experiment gone bad, radiation turns a scientist into a raging green behemoth whenever he becomes agitated. Unable to control his transformations, David Banner searches for a cure as he crosses the country, fugitive-style, with a dogged tabloid reporter on his trail.

An ex con teams up with federal agents to help them with breaking up a moonshine ring.

The owner of a roadside diner and his new helper kill people and feed them to pigs.