The bourgeois couple Esther and Michael have got themselves caught up in a seemingly ironic game of power, provocation and sexuality. Esther is already on the brink of madness when a young artist arrives. Requiem for something which is very small is a psychological horror-drama, with a cultural-political morale, and musical interludes.

In New York City, detective Luigi Mackeroni investigates a string of mysterious penile mutilations at the Hotel Quickie. After Mackeroni attempts to have a tryst with a gigolo he meets in the lobby, a carniverous condom bites off his right testicle and flees, which sets the detective off on a quest to stop the predatory prophylactic once and for all.

Sensing their relationship is crumbling, Christian avoids celebrating Christmas with his girlfriend Julia and heads for Paris.