Investigating mysterious power failures and a death at an underground research centre, The Doctor discovers a colony of Silurians - prehistoric, intelligent reptiles who went into hibernation before man evolved. But now they have woken up, and they are prepared to wipe out mankind with a killer plague to get their planet back.

The adventures of The Doctor, a time-traveling humanoid alien known as a Time Lord. He explores the universe in his TARDIS, a sentient time-traveling spaceship. Its exterior appears as a blue British police box, which was a common sight in Britain in 1963 when the series first aired. Along with a succession of companions, The Doctor faces a variety of foes while working to save civilizations, help ordinary people, and right many wrongs.