After a car crash sends repressed cartoonist Stu into a coma, he and the mischievous Monkeybone, his hilarious alter-ego, wake up in a wacked-out waystation for lost souls. When Monkeybone takes over Stu's body and escapes to wreak havoc on the real world, Stu has to find a way to stop him before his sister pulls the plug on reality forever!

A bank-robbing gang of misfits heads to Mexico with the blueprints for the perfect million-dollar heist, but when one of the crooks wanders into the wrong bar, the thieving cohorts develop a thirst for blood.

The members of WINR (pronounced "Winner") respond when members of the alien Baltan race attack Earth, but the Baltans are only fended off when a gigantic alien, Ultraman Powered, joins with WINR member Kenichi Kai and gives him the power to metamorphose into Ultraman in times of danger. At the end of the first episode Ultraman declares that the Baltans were not completely defeated and that he will remain on Earth to continue the fight. WINR and Ultraman destroy numerous other monsters, but WINR learns that the Baltans were arranging all the battles to learn Ultraman's strengths and weaknesses