God Forgive Us is the dramatic collision of four strangers struggling through drug addiction, existential suicide, terminal illness and death. Portraying various aspects of life and Western society, God Forgive Us chronicles the utter hopelessness that all humans experience regardless of class or social status.

On a USO tour during World War II, entertainer Eddie Sparks needs a partner to round out his act. Soon after hiring performer Dixie Leonard, Eddie decides he wants her out of the show — mostly because she upstages him. Dixie is close to leaving of her own accord, but her uncle, Art Silver, convinces her to stay. As the years and wars go by, Eddie and Dixie experience a tumultuous relationship onstage and off while they continue the act for the troops.