When Sara, a young design student from Iowa, arrives for college in Los Angeles, she is eager to fit in and get to know the big city. Her wealthy roommate, Rebecca, is more than eager to take Sara under her wing and show her the ropes. The two become close, but when Sara begins to branch out and make more friends on campus, Rebecca becomes resentful. Alarmed, Sara moves in with her new boyfriend, causing Rebecca's behavior to take a violent turn.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.