An inventor makes contact with Mars via television. The film is notable for using the 3-D process called Teleview, similar to today's alternating frame 3-D systems. Shown in 3-D only at the Selwyn Theater in New York City, it was previewed as Mars Calling at a trade and press screening on 13 October 1922, premiered as M.A.R.S. on 27 December 1922, and ran through 20 January 1923. A 2-D version was distributed as Radio-Mania in 1923–1924.

Mary Tudor falls in love with a new arrival to court, Charles Brandon. She convinces her brother King Henry VIII to make him his Captain of the Guard. Meanwhile, Henry is determined to marry her off to the aging King Louis XII of France as part of a peace agreement.