After years of being sheltered from the human world, the Turtle brothers set out to win the hearts of New Yorkers and be accepted as normal teenagers through heroic acts. Their new friend April O'Neil helps them take on a mysterious crime syndicate, but they soon get in over their heads when an army of mutants is unleashed upon them.

Inspired by the epic play and big personalities of the Seattle Seahawks, Seahawks vs Monsters channels vintage Japanese Kaiju films but with a PNW lean. When the city of Seattle falls under attack by giant mutated beasts, who better to save the day than the Hawks?