In the 1840s, Ramsey MacKay, the driver for the struggling Wells Fargo mail and freight company, will secure an important contract if he delivers fresh oysters to Buffalo from New York City. When he rescues Justine Pryor and her mother, who are stranded in a broken wagon on his route, he doesn't let them slow him down and gives the ladies an exhilirating ride into Buffalo. He arrives in time to obtain the contract and is then sent by company president Henry Wells to St. Louis to establish a branch office.

Penniless drifter Steve Davis finds young Jimmy Thomas just after his father is killed. The two become friends and Steve looks for work. This brings him to town where teacher June Caldwell has lent money from the school fund to the dishonest Jess Watson, She now desperately needs it back and Steve soon finds himself in the middle of the conflict.

Frank Sr. sells his supplies to Hook, but then Hook has the Bannion Boys bushwhack his wagon to get the money back. Frank is murdered, but Junior gets away. He comes back 10 years later to settle the score as the Singing Cowboy. He finds that Hook is still doing his dirty deeds on the unsuspecting people. Along the way, Frank meets the lovely Jen, who came out in the same wagon train 10 years before.

Anne Gray (Ruth Clifford) runs off with Robert Gordon (William E. Lawrence), believing that he is going to marry her. When they arrive at a hotel, another guest, Langdon Van Kreel (Charles Clary), sees though Gordon's ploy and chases him away.

Following in his dad's footsteps, Shefford devotes himself to freeing his community from the grip of a particularly despotic Mormon sect. In so doing, he rescues his foster sister Fay Larkin, who is coveted by lecherous Mormon elder Wagoner. As was the case in Riders of the Purple Sage, the Mormons are villains simply because they are Mormons.

Lassiter quits the Texas Rangers and spends his life in pursuit of a group of Mormons who kidnapped his married sister. In a town on the Utah border, he meets the Withersteens and falls in love with their daughter, Jane. He also befriends Venters, and helps him track down some bandits who have been rustling the Withersteens' cattle.

Clara Kimball Young stars as Mary Saurin, a British gentlewoman who journeys to South Africa to visit her district-commissioner brother Dick (Henry Woodward). Upon arriving, she is introduced to Major Anthony "Kim" Kinsella (Milton Sills), the most important and influential Army officer in the region. Falling in love with Kinsella, Mary agrees to marry him, but he is apparently killed in a native uprising.

Angela, a lovely young woman of eighteen, lives with her grandmother in Virginia but knows very little about her mother, Lady Eldone, who after the death of Angela's father, moved to Europe and married an English army captain. When Captain Eldone is reported dead, Lady Eldone returns to the United States determined to marry a wealthy man.

Although Spencer Wellington (Howard Hickman) comes from an old, aristocratic family, he carries a bad gene. His doctor, John Rand (George Fisher) recommends that he never marry, but Wellington ignores his advice and weds Grace Valiant (Mary Mersch), who the doctor himself loves. Grace checks out Wellington's family tree and discovers the gene, but she's already pregnant. She gives birth to a child with a birth defect that kills him.

Rimrock Jones is the toughest and most likeable prospector in a thriving Arizona copper camp. Having already been cheated out of several valuable copper strikes, Rimrock nonetheless forges ahead optimistically, hoping to strike it rich just once more. Unfortunately, he can't find anyone to finance his latest expedition -- except for a pretty public stenographer who uses her life savings to grubstake our hero. When Rimrock finally hits pay dirt, he tries to repay the girl for her generosity, only to find that she wants to be a full partner in his copper mine. While he mulls this over, Rimrock's rivals try to bamboozle him out of his mine with the help of a sexy "vamp".

The home of Mrs. Bryson and her two daughters is happy except for the poverty that prevents the girls from sending their sick mother away to the mountains. Both help to support the household, but it is Shirley who feels the responsibility of her mother's approaching death and her worry is evident to all about her. She is employed in a manicure shop frequented by wealthy men and meets Wilfred Templeton, who invites her to dine with him. He questions her about her dejected air and she tells him of her mother's illness. This is Templeton's opportunity, and he asks her to make a bargain with him. He will give her all the money she needs and in return she is to live with him in an apartment which he will establish for her.

Crusading Judge Evans wants to expose the unscrupulous Judge Mordant even though he is engaged to Mordant's daughter, Doris. Hearing of Evan's plan, Mordant devises a scheme of his own and `frames' Evans with five teenage girls and a prostitute.

The father of San Francisco waif Meg runs an illegal liquor club and supports "English" Hal in scheme to blackmail a wealthy girl. Meg is put on probation to Benjamin Merton, father of the girl to be blackmailed. When she discovers her father's plan she reveals all, risking expulsion from her new home and the company of its very attractive son Tom.

The true story of the famed British actor David Garrick and his love for Ada Ingot.