The interwoven stories of three couples which are forced to make life-altering decisions in the face of a disastrous war. Inspired and sometimes blinded by their love, Len, Mia, Andy, Esther, Anna and Erik are as flawed and beautiful as any of the billions who are facing this human-made biological disaster.

Las Vegas showroom magician Cris Johnson has a secret which torments him: he can see a few minutes into the future. Sick of the examinations he underwent as a child and the interest of the government and medical establishment in his power, he lies low under an assumed name in Vegas, performing cheap tricks and living off small-time gambling "winnings." But when a terrorist group threatens to detonate a nuclear device in Los Angeles, government agent Callie Ferris must use all her wiles to capture Cris and convince him to help her stop the cataclysm.

Samantha MacKenzie, the daughter of the president of the United States, arrives at college with a group of Secret Service agents. Samantha, however, resents their presence and decides she wants to attend school just like a normal student. Her father agrees to recall the agents but secretly assigns James, an undercover agent, to pose as a student. They fall in love, but their romance is jeopardized when Samantha learns James' true identity.

Viktor Navorski is a man without a country; his plane took off just as a coup d'etat exploded in his homeland, leaving it in shambles, and now he's stranded at Kennedy Airport, where he's holding a passport that nobody recognizes. While quarantined in the transit lounge until authorities can figure out what to do with him, Viktor simply goes on living – and courts romance with a beautiful flight attendant.

In the midst of a nasty public breakup of married movie stars, a studio publicist scrambles to put a cap on the escalating situation as the couple's latest film has found it's only print kidnapped by the director.