Lizzie McGuire has graduated from middle school and takes a trip to Rome, Italy with her class. And what was supposed to be only a normal trip, becomes a teenager's dream come true.

The story of Padre Pio (1887-1968) from the onset of the stigmata during World War I, when he prayed that soldiers' suffering be his, until his death. The story is told by Emilia, Pio's friend, to a Vatican official reviewing Padre Pio's potential canonization. We watch local people venerate the humble Capuchin monk, we see petty jealousies within the Church almost bring him down, and we experience his decision to build a Home for the Relief of Suffering, a labor of love begun just after World War II. Emilia and her husband Dr. Sanguineti work tirelessly beside the humble but sensible Pio.