John Vandermark (Cumming) has taken in a struggling writer, Sebastian St. Germain (Boreanaz), who overstays his welcome. When John discovers that Sebastian has simply been using him, he turns the tables on his young tenant in an effort to make him work off his rent debt. When Sebastian dies accidentally in the process, John tries to make it up to him by helping him get his book published posthumously. When the book is published, John can't help but take credit for the work of genius... and Sebastian comes back to haunt him.

Workaholic Mike Flaherty is the Deputy Mayor of New York City, serving as Mayor Randall Winston's key strategist and much-needed handler. Mike runs the city with the help of his oddball staff: an anxious and insecure press secretary; a sexist, boorish chief of staff; an impeccably groomed gay activist running minority affairs; a sharp and efficient, man-crazy accountant; and an idealistic young speechwriter. Like Mike, they are all professionally capable but personally challenged.