In 1863, Amsterdam Vallon returns to the Five Points of America to seek vengeance against the psychotic gangland kingpin, Bill the Butcher, who murdered his father years earlier. With an eager pickpocket by his side and a whole new army, Vallon fights his way to seek vengeance on the Butcher and restore peace in the area.

Poet Palmambrogio Guanziroli loses his wallet mere moments after arriving in Milan. He locates the culprit, a photographer nicknamed 'Click' and takes up residence with him until he either gets his money back or his poetry published.

Belle Duke, in order to get revenge on her former lover Philip Bang, organize his jail break. But instead of Philip is the Italian Felice Brianza, AKAS Felix, to escape. Now Felix is obliged to help Philip to escape. He will succeeded and from that moment on the two will join to defraud Belle. The swindle plot become more complicate when Felix falls in love for Philip's daughter.

A bounty hunter name Amen is hired by a group of nuns to recover stolen money. The nuns are female desperadoes in disguise, who want the booty pillaged by an outlaw named Catapult and his gang.

When a shipment of heroin disappears between Italy and New York, a small-time pimp in Milan is framed for the theft. Two professional hitmen are dispatched from New York to find him, but the real thieves want to get rid of him before the New York killers get to him to eliminate any chance of them finding out he's the wrong man.

This fast-moving tale revolves around the kidnaping of a boxer's daughter. The boxer pays the ransom money but the girl is still not released. Her boyfriend decides to get her back his own way.

Mexican's are being smuggled over the border to work as cheap labour for wealthy land baron Fargo. His gang is made up of known criminals with bounties on their heads, this greatly interests two bounty hunters who may have to team up to achieve their goals.

Al arrives in town which is ruled by Lash who has taken possession of one gold mine and is now aiming to get the other which is owned by old Johnny. Al is the only one to support Johnny but still the old man is ambushed and killed.

In 1866 New Mexico, Tom Corbett is a prospector who is called back to his hometown in Laramie Town, Texas at the bequest of a old family friend. Tom arrives in the town to see it under the control of a ruthless and greedy gangster named Jason Scott, who's psychotic and murder-crazed son, Junior Scott, runs it with fear with a posse of thugs who kill anyone who protests their business tactics. Tom finds his brother Jeff, a drunkard looked after by their family maid Mercedes. Tom then tries to persuade Jeff to help him take down the sadistic Scotts so the town can rest easy in peace and harmony again.