Regina Haywood is the newly promoted deputy inspector of East New York, a working-class neighborhood at the edge of Brooklyn. She leads a diverse group of officers and detectives, some of whom are reluctant to deploy her creative methods of serving and protecting in the midst of social upheaval and the early seeds of gentrification.

In a working-class neighborhood outside Los Angeles, Mike and Peggy raise eight boisterous boys. There are 10 people, three bedrooms, one bathroom and everyone in it for themselves.

A self-proclaimed "pesky atheist" is encouraged to help strangers by someone claiming to be God who friends him on Facebook.

A stunning cancer diagnosis spurs Abbie to seek a future girlfriend for fiancé and childhood sweetheart Sam, who's clueless when it comes to dating.

Teenagers Zach and Josh have been best friends their whole lives, but when a gruesome accident leads to a cover-up, the secret drives a wedge between them and propels them down a rabbit hole of escalating paranoia and violence.

In the cruel world of junior high, Edwin suffers in a state of anxiety and alienation alongside his only friend, Flake. Misunderstood by their families and demoralized at school daily, their fury simmers quietly until an idea for vengeance offers them a terrifying release.

During the Cold War, the Soviet Union captures U.S. pilot Francis Gary Powers after shooting down his U-2 spy plane. Sentenced to 10 years in prison, Powers' only hope is New York lawyer James Donovan, recruited by a CIA operative to negotiate his release. Donovan boards a plane to Berlin, hoping to win the young man's freedom through a prisoner exchange. If all goes well, the Russians would get Rudolf Abel, the convicted spy who Donovan defended in court.

Set in the early 1960's in New York City's Public Morals Division, where cops walk the line between morality and criminality as the temptations that come from dealing with all kinds of vice can get the better of them.

Arty leads a secret group of adolescent boys who manipulate the stock market and control New York City. His hold on power is jeopardized when his parents split, causing him to use all his influence to force his dad back home.

Set in downtown New York in 1900, 'The Knick' is centered on the Knickerbocker Hospital and its staff, notably Dr. John Thackery, the hospital's brilliant chief surgeon who pushes medicine's boundaries, pioneering new procedures despite a severe drug addiction.

Catherine Black is a world-famous neurologist at the state-of-the-art medical institution known as "The Cube". Catherine is brilliant, beautiful, and at the top of her game, though she's hiding a secret of her own: she's bipolar. Each week, the doctors on staff attempt to unravel the mysteries of the brain and are constantly challenged by cases never-before-seen on television. The medical stories are moving, bizarre and a visual feast. The personal stories are riveting. The patients have rare, highly visual, often hallucinogenic and startling conditions, which we’ll see through their eyes as Catherine diagnoses and treats them.

Notorious serial killer Joe Carroll, after being found guilty of murdering 14 female students on the Virginia college campus where he taught literature, escapes from death row. The FBI calls former agent Ryan Hardy to consult on the case, as he was the one responsible for Carroll’s capture in 2003. Ryan, working closely with an FBI team, including Mike Weston and FBI Specialist Debra Parker, piece together the ever-growing web of murders orchestrated by the devious Carroll.