Jerry Shaw and Rachel Holloman are two strangers whose lives are suddenly thrown into turmoil by a mysterious woman they have never met. Threatening their lives and family, the unseen caller uses everyday technology to control their actions and push them into increasing danger. As events escalate, Jerry and Rachel become the country's most-wanted fugitives and must figure out what is happening to them.

Chile and Head, two wannabe thugs, get more than they bargained for when they duck into a blues joint while on the run from the cops. The seventy-year-old owner of the club and his staff, each societal misfits in their own right, become hostages and bear witness to an intense journey of self discovery as Chile and Head move down vastly divergent paths.

A high school swim champion with a troubled past enrolls in the U.S. Coast Guard's 'A' School, where legendary rescue swimmer, Ben Randall teaches him some hard lessons about loss, love, and self-sacrifice.

The series follows the ventures of a Missing Persons Unit of the FBI in New York City.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.