When the entire world blacks out for two minutes and seventeen seconds, everyone sees a flash of their own future 6 months from the present. For some, the future is hopeful, while for others, it is unexpected. For a few, it doesn't seem to exist. Knowing their fate will alter each person's life, destinies will be changed.

Following Jigsaw's grisly demise, Detective Mark Hoffman is commended as a hero, but Agent Strahm is suspicious, and delves into Hoffman's past. Meanwhile, another group of people are put through a series of gruesome tests.

Samantha Newly has been a bad, bad girl. But thanks to an 8-day coma, she can't remember a thing. Fortunately her best friend Andrea is by her side with a cocktail and the 4-1-1 on every dirty deed. But the more Sam pieces together her past, the less she likes her old self. Maybe this is a chance to start over and do it all again.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.