Los Serrano is a Spanish television drama comedy which premiered on 22 April 2003 and aired on Telecinco. It tells the story of the Serrano family, who lives in Round Santa Justa No 133, located in the fictional neighborhood of Santa Justa, in the Ribera del Manzanares, in Madrid. The success of the series in Spain and in several other countries in Europe and elsewhere helped launch the career of several young actors and actresses, especially actor and musician Fran Perea, who acts in the series and sings its theme song, "1 más 1 son 7".

Miguel, a young psychiatrist working in Madrid, learns that his wife has just dumped him for no one else than his own father while he's expecting his mother-in-law's visit, who's come to the city on a medical revision, and doesn't know anything about her daughter's affair; to make things worse, one of Miguel's deranged patients has just stolen his wallet. Going to his patient's home to retrieve his wallet he'll meet instead his spontaneous and outspoken hairdresser sister Jasmina, who's bound to change Miguel's ordered, upper-middle-class world for good.

Julia, a real estate agent, finds an enormous amount of money hidden in a dead man's apartment, a stroke of luck that will force her to face the wrath of the very peculiar inhabitants of the condominium, headed by an unscrupulous administrator.