The story of the life and career of the baseball hall of famer, Lou Gehrig.

A mobster's moll leads a newsman, cub reporter and photographer to a scoop.

Detective Guy Johnson's client, Willie Heywood, is framed for murder. While Guy hides him so he can catch the real killer, both of them are nabbed by the police, tried, convicted and sentenced to jail: Guy for a year with Willie to be executed. On the way to jail, Guy comes across a clue and escapes from the police.

One of the last bills signed by President Lincoln authorizes pushing the Union Pacific Railroad across the wilderness to California. But financial opportunist Asa Barrows hopes to profit from obstructing it. Chief troubleshooter Jeff Butler has his hands full fighting Barrows' agent, gambler Sid Campeau; Campeau's partner Dick Allen is Jeff's war buddy and rival suitor for engineer's daughter Molly Monahan. Who will survive the effort to push the railroad through at any cost?