When You're Smiling is distinguished by the presence of several top recording artists of 1950. The wafer-thin plotline concerns the misadventures of Texan Gerald Durham (Jerome Courtland), who arrives in the Big City to learn the ropes of the music business. Durham not only ends up with a recording contract, but also wins heroine Peggy Martin (Lola Albright) in the bargain. So much for the story. The principal selling card of When You're Smiling consists of the guest-star turns by Frankie Laine, Bob Crosby, The Modernaires, The Mills Brothers, Kay Starr and Billy Daniels.

Abilene gunmen are bent on terrorizing the town of Blue Valley and massacring its inhabitants. They have been hired by local druggist Henry Turner, who has discovered gold beneath the town and wishes complete possession.

Gino Monetti is a ruthless Italian-American banker who is engaged in a number of criminal activities. Three of his four grown sons refuse to help their father stay out of prison after he's arrested for his questionable business practices. Three of the sons take over the business but kick their father out. Max, a lawyer, is the only son that stays loyal to his father.