Legless Southern inventor Dr. Arliss Loveless plans to rekindle the Civil War by assassinating President U.S. Grant. Only two men can stop him: gunfighter James West and master-of-disguise and inventor Artemus Gordon. The two must team up to thwart Loveless' plans.

Felicity Porter, a sensitive and intelligent girl from the San Francisco Bay Area, decides to give up a slot at Stanford University's pre-med program to follow her long time crush to college in New York City. Things get even more complicated when she meets her dorm's resident advisor and they fall in love.

A group of French tourists goes on an organized trip to visit the American West. A dream trip from California to Las Vegas, passing through national parks and grandiose sites immortalized by the western.

French nuclear tests irradiate an iguana into a giant monster that viciously attacks freighter ships in the Pacific Ocean. A team of experts, including Niko Tatopoulos, conclude that the oversized reptile is the culprit. Before long, the giant lizard is loose in Manhattan as the US military races to destroy the monster before it reproduces and it's spawn takes over the world.

When guardian angel Seth – who invisibly watches over the citizens of Los Angeles – becomes captivated by Maggie, a strong-willed heart surgeon, he ponders trading in his pure, otherworldly existence for a mortal life with his beloved. The couple embarks on a tender but forbidden romance spanning heaven and Earth.

Homicide detective John Hobbes witnesses the execution of serial killer Edgar Reese. Soon after the execution the killings start again, and they are very similar to Reese's style.

Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.

Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.

After many years spent at the “Cheers” bar, Frasier moves back home to Seattle to work as a radio psychiatrist after his policeman father gets shot in the hip on duty.