At midnight on Walpurgis Night, an English clerk, Renfield, arrives at Count Dracula's castle in the Carpathian Mountains. After signing papers to take over a ruined abbey near London, Dracula drives Renfield mad and commands obedience. Renfield escorts the boxed count on a death ship to London. From there, the Count is introduced into the society of his neighbor, Dr. Seward, who runs an asylum. Dracula makes short work of family friend Lucia Weston, then begins his assault on Eva Seward, the doctor's daughter. A visiting expert in the occult, Van Helsing, recognizes Dracula for who he is, and there begins a battle for Eva's body and soul.

British estate agent Renfield travels to Transylvania to meet with the mysterious Count Dracula, who is interested in leasing a castle in London and is, unbeknownst to Renfield, a vampire. After Dracula enslaves Renfield and drives him to insanity, the pair sail to London together, and as Dracula begins preying on London socialites, the two become the subject of study for a supernaturalist professor, Abraham Van Helsing.