Federal agent Alexandra Barnes believes that Catherine Petersen is a serial killer who marries rich men and then murders them for their money. But since Catherine is seemingly a master of disguise and has multiple identities, Alexandra can't prove anything with conventional detective work. With no other option, she goes undercover, pursuing the same man as Catherine, and hoping that Catherine will slip up and reveal her true identity.

The life of Fanny Brice, famed comedian and entertainer of the early 1900s. We see her rise to fame as a Ziegfeld girl, her subsequent career, and her personal life, particularly her relationship with Nick Arnstein.