Based on a true story, Jason and Shirley recreates the 1966 power struggle between Jewish, Oscar-winning documentary filmmaker Shirley Clarke and her subject, Jason Holiday, a fierce black gay queen over a 12-hour marathon filming session which gave rise to Clarke's iconic documentary Portrait of Jason.

Strike is a young city drug pusher under the tutelage of drug lord Rodney Little. When a night manager at a fast-food restaurant is found with four bullets in his body, Strike’s older brother turns himself in as the killer. Detective Rocco Klein doesn’t buy the story, however, setting out to find the truth, and it seems that all the fingers point toward Strike & Rodney.