Three years after his wife, acclaimed photographer Isabelle Reed, dies in a car crash, Gene keeps everyday life going with his shy teenage son, Conrad. A planned exhibition of Isabelle’s photographs prompts Gene's older son, Jonah, to return to the house he grew up in - and for the first time in a very long time, the father and the two brothers are living under the same roof.

Inspired by the award-winning documentary, this medical drama is set in the busiest and most notorious ER in the nation where the extraordinary staff confront a challenged system in order to protect their ideals and the patients who need them the most.