After Doug picks up hitchhiking Rosco with his truck, they are mistaken for two bank robbers by the traffic police. They manage to escape only to be confused for two secret agents while trying to take a flight at the airport.

While everyone knows you can't fight City Hall, there are those who, for whatever reason, can't resist the challenge. Three slightly disturbed psychiatric patients decide to take on the government. What ensues includes car chases, a ferry boat hijacking, strip-teases and lots of fun!