A man glimpses the future Fate has planned for him – and chooses to fight for his own destiny. Battling the powerful Adjustment Bureau across, under and through the streets of New York, he risks his destined greatness to be with the only woman he's ever loved.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

The close-knit Walker family deals with struggles and triumphs.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.