Albert is an introverted travel agent living a lonely life in New York. When Louie, his best friend from childhood, appears having just escaped from prison, Albert's quiet existence is permanently disrupted. what ensues is one long, crazy night in New York that will change both their lives forever.

The film portrays life of New York City's Lower East Side inhabitants. Introvert therapist Betty is befriended with Chinese immigrant Lu Lu, leftist radical Che is also Lu Lu's friend. Italian immigrant and wife of supervisor of building where they all live, Marta, is having an affair with her neighbour Frankie who likes scams. One of his scams goes terribly wrong.