It is 1957. J.C. Cullen is a young man from a small town, with a talent for winning at craps, who leaves for the big city to work as a professional gambler. While there, he breaks the bank at a private craps game at the Gem Club, owned by George Cole, and falls in love with two women, one of them Cole's wife.

Harvey Keitel plays Penfield Gruber, a once great scientist, reduced to managing a sleazy hotel. Gruber monitors the daily comings and goings of his tenants, mainly for his own interest, until underworld figures ask him to spy on a suspected double-crosser. While watching the man, Gruber overhears a murder plot.